Classification and genetic targeting of cell types in the primary taste and premotor center of the adult Drosophila brain.

ABSTRACT: Neural circuits carry out complex computations that allow animals to evaluate food, select mates, move toward attractive stimuli, and move away from threats. In insects, the subesophageal zone (SEZ) is a brain region that receives gustatory, pheromonal, and mechanosensory inputs and contributes to the control of diverse behaviors, including feeding, grooming, and locomotion. Despite its importance in sensorimotor transformations, the study of SEZ circuits has been hindered by limited knowledge of the underlying diversity of SEZ neurons. Here, we generate a collection of split-GAL4 lines that provides precise genetic targeting of 138 different SEZ cell types in adult Drosophila melanogaster, comprising approximately one third of all SEZ neurons. We characterize the single-cell anatom

SUBMITTER: Sterne GR 

PROVIDER: S-EPMC8445619 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature