KIF20B Promotes Cell Proliferation and May Be a Potential Therapeutic Target in Pancreatic Cancer.
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ABSTRACT:
SUBMITTER: Chen J
PROVIDER: S-EPMC8445734 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Publications
KIF20B Promotes Cell Proliferation and May Be a Potential Therapeutic Target in Pancreatic Cancer.
Chen Jing J Zhao Cui-Cui CC Chen Fei-Ran FR Feng Guo-Wei GW Luo Fei F Jiang Tao T
Journal of oncology 20210909
KIFs have been reported to play a critical role in a variety of tumors, and KIF20B is a protein in KFIs. In this research, KIF20B was highly expressed in the GEO database and our hospital's data, and high expression of KIF20B suggested poor prognosis. We detect the expression of KIF20B in pancreatic cancer and adjacent normal tissues using immunohistochemistry. Knockdown of KIF20B in pancreatic cancer cell lines, PANC-1 and BxPC-3 cells, inhibited cell proliferation which are detected by colony ...[more]
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