Normobaric oxygen may correct chronic cerebral ischemia-mediated EEG anomalies.

ABSTRACT:

Aims

To explore the safety and efficacy of normobaric oxygen (NBO) on correcting chronic cerebral ischemia (CCI) and related EEG anomalies.

Methods

This prospective randomized trial (NCT03745092) enrolled 50 cases of CCI patients, which were divided into NBO (8 L/min of oxygen supplement) group and control group (room air) randomly, and also enrolled 21 healthy volunteers. Two times of 30-min EEG recordings with the interval of 45min of NBO or room air were analyzed quantitatively.

Results

The CCI-mediated EEG presented with two patterns of electrical activities: high-power oscillations (high-power EEG, n = 26) and paroxysmal slow activities under the normal-power background (normal-power EEG, n = 24). The fronto-central absolute power (AP) of the beta, alpha, theta,

SUBMITTER: Ding JY 

PROVIDER: S-EPMC8446210 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature