Tumor immunity is related to ¹⁸ F-FDG uptake in thymic epithelial tumor.

ABSTRACT:

Background

2-deoxy-2-[fluorine-18] fluoro-d-glucose (¹⁸ F-FDG) positron emission tomography (¹⁸ F-FDG-PET) is a convenient modality to assess the metabolic activity within tumor cells. However, there is no consensus regarding the relationship between ¹⁸ F-FDG uptake and the immune environment in thymic epithelial tumors (TETs). We conducted a clinicopathological study to elucidate the relationship between ¹⁸ F-FDG uptake and programmed death ligands 1 and 2 (PD-L1/PD-L2) expression in patients with TETs.

Methods

A total of 108 patients with histologically confirmed TETs classified as thymomas or thymic carcinomas who underwent surgical resection or biopsy or needle biopsy and ¹⁸ F-FDG PET before any treatment between Aug

SUBMITTER: Imai H 

PROVIDER: S-EPMC8446555 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature