Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: national prospective cohort study.

ABSTRACT:

Objectives

To derive and validate risk prediction algorithms to estimate the risk of covid-19 related mortality and hospital admission in UK adults after one or two doses of covid-19 vaccination.

Design

Prospective, population based cohort study using the QResearch database linked to data on covid-19 vaccination, SARS-CoV-2 results, hospital admissions, systemic anticancer treatment, radiotherapy, and the national death and cancer registries.

Settings

Adults aged 19-100 years with one or two doses of covid-19 vaccination between 8 December 2020 and 15 June 2021.

Main outcome measures

Primary outcome was covid-19 related death. Secondary outcome was covid-19 related hospital admission. Outcomes were assessed from 14 days after each vaccination dose. Models were

SUBMITTER: Hippisley-Cox J 

PROVIDER: S-EPMC8446717 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature