Lack of resistance to macrolides in Mycoplasma genitalium detected in South African pregnant women.

ABSTRACT:

Background

Azithromycin regimens have been considered first-line treatment for Mycoplasma genitalium (M. genitalium), a sexually transmitted infection (STI) associated with adverse pregnancy outcomes. However, recent years have seen rapid emergence of macrolide resistance in M. genitalium as a result of widespread administration of azithromycin. Currently, there are limited data on macrolide resistance in pregnant women from KwaZulu-Natal (KZN), South Africa. This study investigated the prevalence of M. genitalium and emerging patterns of macrolide resistance in pregnant women from KZN.

Methods

This was a sub-study of a larger study which involved laboratory-based detection of STIs in pregnant women. In the main study, pregnant women provided urin

SUBMITTER: Naicker M 

PROVIDER: S-EPMC8447758 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature