Non-invasive neurally adjusted ventilatory assist in preterm infants with RDS: effect of changing NAVA levels.

ABSTRACT: We aimed to examine the effect of changing levels of support (NAVA level) during non-invasive neurally adjusted ventilatory assist (NIV-NAVA) in preterm infants with respiratory distress syndrome (RDS) on electrical diaphragm activity. This is a prospective, single-centre, interventional, exploratory study in a convenience sample. Clinically stable preterm infants supported with NIV-NAVA for RDS were eligible. Patients were recruited in the first 24 h after the start of NIV-NAVA. Following a predefined titration protocol, NAVA levels were progressively increased starting from a level of 0.5 cmH₂O/µV and with increments of 0.5 cmH₂O/µV every 3 min, up to a maximum level of 4.0 cmH₂O/µV. We measured the evolution of peak inspiratory pressure and the electrica

SUBMITTER: Lefevere J 

PROVIDER: S-EPMC8447891 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature