Maternal age at last birth and leukocyte telomere length in a nationally representative population of perimenopausal and postmenopausal women.

ABSTRACT:

Objective

The primary aim of this study was to evaluate if maternal age at birth of last child is associated with leukocyte telomere length in a nationally representative population of perimenopausal and postmenopausal women.

Methods

We conducted a cross-sectional analysis of 1,232 women from the National Health and Nutrition Examination Survey to examine maternal age at last birth and telomere length, surveyed between 1999 and 2002. We included perimenopausal and postmenopausal women age 40 years and older. Maternal age at last live birth was self-reported, and leukocyte telomere length was measured using quantitative polymerase chain reaction. We calculated least-squares geometric mean telomere length across categories of maternal age adjusted for age, race/ethnicity, numb

SUBMITTER: Latour CD 

PROVIDER: S-EPMC8448037 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature