Genetic Context of optrA and poxtA in Florfenicol-Resistant Enterococci Isolated from Flowing Surface Water in Switzerland.
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SUBMITTER: Biggel M
PROVIDER: S-EPMC8448137 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
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Genetic Context of <i>optrA</i> and <i>poxtA</i> in Florfenicol-Resistant Enterococci Isolated from Flowing Surface Water in Switzerland.
Biggel Michael M Nüesch-Inderbinen Magdalena M Jans Christoph C Stevens Marc J A MJA Stephan Roger R
Antimicrobial agents and chemotherapy 20210712 10
Linezolid is an important last-resort antibiotic for the treatment of multidrug-resistant enterococci. The aim of this study was to further characterize the genetic context of <i>optrA</i> and <i>poxtA</i> in 10 florfenicol-resistant enterococci isolated from flowing surface water. In most genomes, <i>optrA</i> and <i>poxtA</i> were embedded in transposition units integrated into plasmids or into the chromosomal <i>radC</i>. For the first time, a chromosomally integrated <i>optrA</i> in an Enter ...[more]
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