Dosage individualization proposed for anti-gout medications among the patients with gout.

ABSTRACT:

Background

The conventional one-size-fits-all approach has been criticized for almost all drugs used especially for chronic diseases, including gout. The present study was aimed to explore the need of individualization and optimization of the dose of anti-gout medications among gout patients.

Methods

Cross-sectional study was carried out among 384 randomly selected new gout patients visiting two gout treatment centers at Lalitpur Metropolitan City, Nepal and who were taking antigout medications. Patients not taking anti-gout medications and not showing willingness to participate were excluded. The eGFR was calculated with the CKD Epidemiology Collaboration (CKD-EPI) creatinine equation (2009). Doses to be individualized were decided based on the Renal Drug Handbook and verif

SUBMITTER: Sapkota B 

PROVIDER: S-EPMC8448378 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature