The Etiology of Childhood Pneumonia in Mali: Findings From the Pneumonia Etiology Research for Child Health (PERCH) Study.

ABSTRACT:

Background

We present findings from the Pneumonia Etiology Research for Child Health (PERCH) site in Bamako, Mali.

Methods

Cases were patients 28 days to 59 months of age, admitted to hospital with severe or very severe pneumonia (2005 World Health Organization definition). Community controls were frequency matched by age. Both provided nasopharyngeal and oropharyngeal swabs for multiplex polymerase chain reaction and Streptococcus pneumoniae culture. Cases underwent blood culture and induced sputum culture for Mycobacterium tuberculosis. A subset had pleural fluid and lung aspirates collected for culture and polymerase chain reaction. Primary analyses included participants with negative or unknown HIV status (HIV-) and cases with abnormal chest radiographs (CXR+). Cases and

SUBMITTER: Tapia MD 

PROVIDER: S-EPMC8448406 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature