Long-term Dietary Flavonoid Intake and Subjective Cognitive Decline in US Men and Women.

ABSTRACT:

Objective

To prospectively examine the associations between long-term dietary flavonoids and subjective cognitive decline (SCD).

Methods

We followed 49,493 women from the Nurses' Health Study (NHS) (1984-2006) and 27,842 men from the Health Professionals Follow-Up Study (HPFS) (1986-2002). Poisson regression was used to evaluate the associations between dietary flavonoids (flavonols, flavones, flavanones, flavan-3-ols, anthocyanins, polymeric flavonoids, and proanthocyanidins) and subsequent SCD. For the NHS, long-term average dietary intake was calculated from 7 repeated semiquantitative food frequency questionnaires (SFFQs), and SCD was assessed in 2012 and 2014. For the HPFS, average dietary intake was calculated from 5 repeated SFFQs, and SCD was assessed in 2008 and 201

SUBMITTER: Yeh TS 

PROVIDER: S-EPMC8448553 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature