Breast and Lung Effusion Survival Score Models: Improving Survival Prediction in Patients With Malignant Pleural Effusion and Metastasis.

ABSTRACT:

Background

Evidence-based guidelines recommend management strategies for malignant pleural effusions (MPEs) based on life expectancy. Existent risk-prediction rules do not provide precise individualized survival estimates.

Research question

Can a newly developed continuous risk-prediction survival model for patients with MPE and known metastatic disease provide precise survival estimates?

Study design and methods

Single-center retrospective cohort study of patients with proven malignancy, pleural effusion, and known metastatic disease undergoing thoracentesis from 2014 through 2017. The outcome was time from thoracentesis to death. Risk factors were identified using Cox proportional hazards models. Effect-measure modification (EMM) was tested using the Mantel-Cox test

SUBMITTER: Molina S 

PROVIDER: S-EPMC8449006 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature