Assessment of Allergic and Anaphylactic Reactions to mRNA COVID-19 Vaccines With Confirmatory Testing in a US Regional Health System.

ABSTRACT:

Importance

As of May 2021, more than 32 million cases of COVID-19 have been confirmed in the United States, resulting in more than 615 000 deaths. Anaphylactic reactions associated with the Food and Drug Administration (FDA)-authorized mRNA COVID-19 vaccines have been reported.

Objective

To characterize the immunologic mechanisms underlying allergic reactions to these vaccines.

Design, setting, and participants

This case series included 22 patients with suspected allergic reactions to mRNA COVID-19 vaccines between December 18, 2020, and January 27, 2021, at a large regional health care network. Participants were individuals who received at least 1 of the following International Statistical Classification of Diseases and Related Health Problems, Tenth Revision anaphyl

SUBMITTER: Warren CM 

PROVIDER: S-EPMC8449279 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature