Ontology highlight
ABSTRACT:
SUBMITTER: Lin HW
PROVIDER: S-EPMC8449312 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Lin Hsuan-Wen HW Chen Chun-Chao CC de Belle J Steven JS Tully Tim T Chiang Ann-Shyn AS
Proceedings of the National Academy of Sciences of the United States of America 20210901 37
Episodic events are frequently consolidated into labile memory but are not necessarily transferred to persistent long-term memory (LTM). Regulatory mechanisms leading to LTM formation are poorly understood, however, especially at the resolution of identified neurons. Here, we demonstrate enhanced LTM following aversive olfactory conditioning in <i>Drosophila</i> when the transcription factor cyclic AMP response element binding protein A (CREBA) is induced in just two dorsal-anterior-lateral (DAL ...[more]