Increasing and decreasing interregional brain coupling increases and decreases oscillatory activity in the human brain.

ABSTRACT: The origins of oscillatory activity in the brain are currently debated, but common to many hypotheses is the notion that they reflect interactions between brain areas. Here, we examine this possibility by manipulating the strength of coupling between two human brain regions, ventral premotor cortex (PMv) and primary motor cortex (M1), and examine the impact on oscillatory activity in the motor system measurable in the electroencephalogram. We either increased or decreased the strength of coupling while holding the impact on each component area in the pathway constant. This was achieved by stimulating PMv and M1 with paired pulses of transcranial magnetic stimulation using two different patterns, only one of which increases the influence exerted by PMv over M1. While the stimulation protoco

SUBMITTER: Sel A 

PROVIDER: S-EPMC8449322 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature