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Identifying asymptomatic spreaders of antimicrobial-resistant pathogens in hospital settings.


ABSTRACT: Antimicrobial-resistant organisms (AMROs) can colonize people without symptoms for long periods of time, during which these agents can spread unnoticed to other patients in healthcare systems. The accurate identification of asymptomatic spreaders of AMRO in hospital settings is essential for supporting the design of interventions against healthcare-associated infections (HAIs). However, this task remains challenging because of limited observations of colonization and the complicated transmission dynamics occurring within hospitals and the broader community. Here, we study the transmission of methicillin-resistant Staphylococcus aureus (MRSA), a prevalent AMRO, in 66 Swedish hospitals and healthcare facilities with inpatients using a data-driven, agent-based model informed by deidentified r

SUBMITTER: Pei S 

PROVIDER: S-EPMC8449327 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature