Compositional distinction of gut microbiota between Han Chinese and Tibetan populations with liver cirrhosis.

ABSTRACT:

Background

Liver cirrhosis (LC) is caused by numerous chronic liver diseases and its complications are associated with qualitative and quantitative alterations of the gut microbiota. Previous studies have revealed the characteristics of gut microbiota in Han Chinese patients with LC and different compositions of gut microbiota were reported between the Tibetan and Han Chinese populations. This study was designed to evaluate the unique features of the gut microbiota of Tibetans and compare the differences of gut microbiota between Tibetan and Han Chinese patients with LC.

Methods

Thirty-six patients with liver cirrhosis and nineteen healthy volunteers, from both Tibetan and Han Chinese populations, were enrolled and fecal samples were collected for 16S rRNA gene sequencing an

SUBMITTER: Huan H 

PROVIDER: S-EPMC8449536 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature