Route of oxytocin administration for preventing blood loss at caesarean section: a systematic review with meta-analysis.

ABSTRACT:

Objectives

Assess the effects of different routes of prophylactic oxytocin administration for preventing blood loss at caesarean section (CS).

Design

Systematic review and meta-analysis.

Methods

Medline, EMBASE, CINAHL, Cochrane Library, BVS, SciELO and Global Index Medicus were searched through 24 May 2020 for randomised controlled trials (RCTs) comparing different routes of prophylactic oxytocin administration during CS. Study selection, data extraction and quality assessment were conducted by two investigators independently. We pooled results in fixed effects meta-analyses and calculated average risk ratio (RR), mean difference (MD) and 95% CI. We used GRADE to assess the overall quality of evidence for each outcome.

Results

Three trials (180 women) were inc

SUBMITTER: Torloni MR 

PROVIDER: S-EPMC8449971 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature