Malaria infection prevalence and sensitivity of reactive case detection in Zanzibar.

ABSTRACT:

Background

Reactive case detection (RCD) is a commonly used strategy for malaria surveillance and response in elimination settings. Many approaches to RCD assume detectable infections are clustered within and around homes of passively detected cases (index households), which has been evaluated in a number of settings with disparate results.

Methods

Household questionnaires and diagnostic testing were conducted following RCD investigations in Zanzibar, Tanzania, including the index household and up to 9 additional neighboring households.

Results

Of 12,487 participants tested by malaria rapid diagnostic test (RDT), 3·2% of those residing in index households and 0·4% of those residing in non-index households tested positive (OR = 8·4; 95%CI: 5·7, 12·5). Of 6,281 particip

SUBMITTER: Stuck L 

PROVIDER: S-EPMC8450816 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature