Interaction of Caffeine with Model Lipid Membranes.
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ABSTRACT:
SUBMITTER: Tavagnacco L
PROVIDER: S-EPMC8450902 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Publications
Interaction of Caffeine with Model Lipid Membranes.
Tavagnacco Letizia L Corucci Giacomo G Gerelli Yuri Y
The journal of physical chemistry. B 20210901 36
Caffeine is not only a widely consumed active stimulant, but it is also a model molecule commonly used in pharmaceutical sciences. In this work, by performing quartz-crystal microbalance and neutron reflectometry experiments we investigate the interaction of caffeine molecules with a model lipid membrane. We determined that caffeine molecules are not able to spontaneously partition from an aqueous environment, enriched in caffeine, into a bilayer. Caffeine could be however included in solid-supp ...[more]
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