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Phenolic constituents from twigs of Aleurites fordii and their biological activities.

ABSTRACT: Three new neolignan glycosides (1-3), a new phenolic glycoside (15), and a new cyanoglycoside (16) were isolated and characterized from the twigs of Aleurites fordii together with 14 known analogues (4-14 and 17-19). The structural elucidation of the new compounds was performed through the analysis of their NMR, HRMS, and ECD spectra and by chemical methods. All isolated compounds were tested for their antineuroinflammatory and neuroprotective activities.

SUBMITTER: Park KJ

PROVIDER: S-EPMC8450942 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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Phenolic constituents from twigs of Aleurites fordii and their biological activities.

Park Kyoung Jin KJ Suh Won Se WS Yoon Da Hye DH Kim Chung Sub CS Kim Sun Yeou SY Lee Kang Ro KR

Beilstein journal of organic chemistry 20210907

Three new neolignan glycosides (1-3), a new phenolic glycoside (15), and a new cyanoglycoside (16) were isolated and characterized from the twigs of Aleurites fordii together with 14 known analogues (4-14 and 17-19). The structural elucidation of the new compounds was performed through the analysis of their NMR, HRMS, and ECD spectra and by chemical methods. All isolated compounds were tested for their antineuroinflammatory and neuro ...[more]

PMID: 34621396

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