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A visible-light-induced, metal-free bis-arylation of 2,5-dichlorobenzoquinone.

ABSTRACT: A metal-free protocol for the direct bis-arylation of 2,5-dichlorobenzoquinone with aryldiazonium salts is reported. The reactive salts are generated in situ and converted to radicals through irradiation with visible light. Reaction products precipitate from the solvent, eliminating the need for purification and thus providing a novel green method for the synthesis of versatile bis-electrophiles.

SUBMITTER: Winant P

PROVIDER: S-EPMC8450952 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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A visible-light-induced, metal-free bis-arylation of 2,5-dichlorobenzoquinone.

Winant Pieterjan P Dehaen Wim W

Beilstein journal of organic chemistry 20210906

A metal-free protocol for the direct bis-arylation of 2,5-dichlorobenzoquinone with aryldiazonium salts is reported. The reactive salts are generated in situ and converted to radicals through irradiation with visible light. Reaction products precipitate from the solvent, eliminating the need for purification and thus providing a novel green method for the synthesis of versatile bis-electrophiles. ...[more]

PMID: 34621394

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