Effectiveness and safety of ivermectin in the treatment of COVID-19: protocol for a systematic review and meta-analysis.

ABSTRACT:

Introduction

Ivermectin is a drug with antiviral properties and has been proposed as an alternative treatment for patients with COVID-19, in some countries; however, there is limited evidence to support its clinical use. Accordingly, the aim of this review and meta-analysis is to obtain superior evidence on the effectiveness and safety of ivermectin in treatment of COVID-19.

Methods and analysis

We will search in the medical databases and International Clinical Trials Registry Platform databases for randomised clinical trials and quasi-randomised trials published from December 2019. The criteria for inclusion are that infection needs to be confirmed by a real-time PCR or serology test, and the effect of ivermectin has been compared with placebo, symptomatic treatment or no t

SUBMITTER: Machado MLL 

PROVIDER: S-EPMC8450968 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature