Determinants of the postprandial triglyceride response to a high-fat meal in healthy overweight and obese adults.

ABSTRACT:

Background

Dyslipidemia is a feature of impaired metabolic health in conjunction with impaired glucose metabolism and central obesity. However, the contribution of factors to postprandial lipemia in healthy but metabolically at-risk adults is not well understood. We investigated the collective contribution of several physiologic and lifestyle factors to postprandial triglyceride (TG) response to a high-fat meal in healthy, overweight and obese adults.

Methods

Overweight and obese adults (n = 35) underwent a high-fat meal challenge with blood sampled at fasting and hourly in the 4-hour postprandial period after a breakfast containing 50 g fat. Incremental area under the curve (iAUC) and postprandial magnitude for TG were calculated and data analyzed using a linear model with

SUBMITTER: Wilson SM 

PROVIDER: S-EPMC8451105 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature