Sources of variation of DNA methylation in rainbow trout: combined effects of temperature and genetic background.

ABSTRACT: Phenotypic plasticity is a key component of the ability of organisms to respond to changing environmental conditions. In this study, we aimed to study the establishment of DNA methylation marks in response to an environmental stress in rainbow trout and to assess whether these marks depend on the genetic background. The environmental stress chosen here was temperature, a known induction factor of epigenetic marks in fish. To disentangle the role of epigenetic mechanisms such as DNA methylation in generating phenotypic variations, nine rainbow trout isogenic lines with no genetic variability within a line were used. For each line, half of the eggs were incubated at standard temperature (11°C) and the other half at high temperature (16°C), from eyed-stage to hatching. In order to gain a firs

SUBMITTER: Lallias D 

PROVIDER: S-EPMC8451451 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature