Testicular volume in infertile versus fertile white-European men: a case-control investigation in the real-life setting.

ABSTRACT: Testicular volume (TV) is considered a good clinical marker of hormonal and spermatogenic function. Accurate reference values for TV measures in infertile and fertile men are lacking. We aimed to assess references values for TV in white-European infertile men and fertile controls. We analyzed clinical and laboratory data from 1940 (95.0%) infertile men and 102 (5.0%) fertile controls. Groups were matched by age using propensity score weighting. TV was assessed using a Prader orchidometer (PO). Circulating hormones and semen parameters were investigated in every male. Descriptive statistics, Spearman's correlation, and logistic regression models tested potential associations between PO-estimated TV values and clinical variables. Receiver operating characteristic (ROC) curves were used to fi

SUBMITTER: Boeri L 

PROVIDER: S-EPMC8451491 | biostudies-literature | 2021 Sep-Oct

REPOSITORIES: biostudies-literature