Perioperative albuminuria and clinical model to predict acute kidney injury in paediatric cardiac surgery.

ABSTRACT:

Background

AKI is an important complication post cardiac surgery in children. An early diagnosis can help in mitigating complications and allow for prognostication. Urinary albumin:creatinine ratio (ACR) as a biomarker can provide a cheaper and more accessible AKI risk assessment and prediction. There is a paucity of paediatric literature regarding its utility.

Methods

This was a prospective observational study, enrolling all children aged 1 month to 18 years, who underwent cardiac surgery, with use of cardiopulmonary bypass. Cohort was divided into groups < 2 years and ≥ 2 years for analyses to account for differences in physiological albumin excretion with age.

Results

Of 143 children enrolled in the study, 36 developed AKI. In both age groups, the post-operative AC

SUBMITTER: Nautiyal A 

PROVIDER: S-EPMC8451727 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature