Research Review: Developmental origins of depression - a systematic review and meta-analysis.

ABSTRACT:

Background

Many observational studies have found a direct association between adverse in utero, perinatal and postnatal exposures and offspring's depression. These findings are consistent with the 'developmental origins of disease hypothesis'. But no review has comprehensively summarized the roles of these exposures. This review aims to systematically scrutinize the strength of associations between individual prenatal, perinatal, and postnatal exposures and subsequent depression in offspring.

Methods

We conducted a systematic review and meta-analysis to synthesize the literature from the EMBASE, HealthStar, PsychoInfo, and Medline databases since their inception to September 1, 2019. English language articles on population-based prospective cohort studies examining the assoc

SUBMITTER: Su Y 

PROVIDER: S-EPMC8451906 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature