Sex differences in parent-offspring recurrence of attention-deficit/hyperactivity disorder.

ABSTRACT:

Background

Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental disorder sharing genetic risk factors with other common psychiatric disorders. However, intergenerational recurrence patterns of ADHD from parents to sons and daughters are not known. We aimed to examine the risk of ADHD in offspring of parents with ADHD and parents with other psychiatric disorders by parental and offspring sex, using parents without the specific disorders as comparison.

Methods

In a generation study linking data from several population-based registries, all Norwegians born 1967-2011 (n = 2,486,088; Medical Birth Registry of Norway) and their parents were followed to 2015. To estimate intergenerational recurrence risk, we calculated prevalence differences (PD)

SUBMITTER: Solberg BS 

PROVIDER: S-EPMC8451909 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature