Management and Long-Term Outcomes of Advanced Stage Thymoma in the United States.

ABSTRACT:

Background

Thymomas are rare tumors, with limited data regarding treatment of advanced stage disease. Although surgical resection is the mainstay of treatment, the role of additional therapy remains controversial. Our objectives were to describe treatment strategies for stage III/IV thymoma in the United States and compare survival outcomes among treatment approaches.

Methods

We identified Masaoka stage III/IV thymoma reported in the National Cancer Database between 2004 and 2016. Frequencies of treatment with surgery, chemotherapy, radiation, and combinations were calculated. Five-year overall survival was compared using the Kaplan-Meier method and log-rank test. Risk-adjusted proportional hazards modeling compared mortality between treatment regimens.

Results

A tota

SUBMITTER: Khorfan R 

PROVIDER: S-EPMC8452232 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature