Quantification of the spread of SARS-CoV-2 variant B.1.1.7 in Switzerland.

ABSTRACT:

Background

In December 2020, the United Kingdom (UK) reported a SARS-CoV-2 Variant of Concern (VoC) which is now named B.1.1.7. Based on initial data from the UK and later data from other countries, this variant was estimated to have a transmission fitness advantage of around 40-80 % (Volz et al., 2021; Leung et al., 2021; Davies et al., 2021).

Aim

This study aims to estimate the transmission fitness advantage and the effective reproductive number of B.1.1.7 through time based on data from Switzerland.

Methods

We generated whole genome sequences from 11.8 % of all confirmed SARS-CoV-2 cases in Switzerland between 14 December 2020 and 11 March 2021. Based on these data, we determine the daily frequency of the B.1.1.7 variant and quantify the variant's transmission fitn

SUBMITTER: Chen C 

PROVIDER: S-EPMC8452947 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature