Ontology highlight
ABSTRACT:
SUBMITTER: Newman JG
PROVIDER: S-EPMC8453797 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Newman Jason G JG Hall Mary A MA Kurley Sarah J SJ Cook Robert W RW Farberg Aaron S AS Geiger Jessica L JL Koyfman Shlomo A SA
Head & neck 20210607 9
Standard of care for high-risk cutaneous squamous cell carcinoma (cSCC) is surgical excision of the primary lesion with clear margins when possible, and additional resection of positive margins when feasible. Even with negative margins, certain high-risk factors warrant consideration of adjuvant therapy. However, which patients might benefit from adjuvant therapy is unclear, and supporting evidence is conflicting and limited to mostly small retrospective cohorts. Here, we review literature from ...[more]