Validation of multiple equations for estimating low-density lipoprotein cholesterol levels in Korean adults.

ABSTRACT:

Background

Limited data are available for validation of low-density lipoprotein cholesterol (LDL) calculation (LDL_cal) in the adult Korean population. The aim of this study was to develop and validate a new equation for LDL_cal and to compare it with previous such equations in a Korean population.

Methods

A new equation for LDL_cal was developed (LDL_Choi). LDL_Choi and 11 other previously published equations were applied and compared with directly measured LDL concentration (LDL_direct) in a development cohort (population 1), an independent validation cohort in the same laboratory (population 2), and the Korea National Health and Nutrition Examination Survey 2017 cohort (population 3).

Results

Among the 12

SUBMITTER: Choi R 

PROVIDER: S-EPMC8453999 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature