Prevalence of persistent symptoms after treatment for lyme borreliosis: A prospective observational cohort study.

ABSTRACT:

Background

Concerns about long-lasting symptoms attributed to Lyme borreliosis (LB) are widespread in the Western world, while such symptoms are highly prevalent in the general population.

Methods

In the largest prospective study to date, adults with physician-confirmed LB were included at the start of antibiotic treatment. Primary outcomes, prevalence of persistent symptoms and symptom severity, were assessed using three-monthly standardised questionnaires during one year. Persistent symptoms were defined as impaired scores for fatigue (CIS, subscale fatigue), cognitive impairment (CFQ) or pain (SF-36, subscale bodily pain) ≥6 months, with onset <6 months. Outcomes were compared with a longitudinal general population and a tick-bite cohort without LB as a reference.

Find

SUBMITTER: Ursinus J 

PROVIDER: S-EPMC8454881 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature