Risk factor for breast cancer development under exposure to bovine leukemia virus in Colombian women: A case-control study.

ABSTRACT: Viruses have been implicated in cancer development in both humans and animals. The role of viruses in cancer is typically to initiate cellular transformation through cellular DNA damage, although specific mechanisms remain unknown. Silent and long-term viral infections need to be present, in order to initiate cancer disease. In efforts to establish a causative role of viruses, first is needed to demonstrate the strength and consistency of associations in different populations. The aim of this study was to determine the association of bovine leukemia virus (BLV), a causative agent of leukemia in cattle, with breast cancer and its biomarkers used as prognosis of the severity of the disease (Ki67, HER2, hormonal receptors) in Colombian women. An unmatched, observational case-control study was

SUBMITTER: Olaya-Galan NN 

PROVIDER: S-EPMC8454960 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature