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Role of juvenile hormone receptor Methoprene-tolerant 1 in silkworm larval brain development and domestication.


ABSTRACT: The insect brain is the central part of the neurosecretory system, which controls morphology, physiology, and behavior during the insect's lifecycle. Lepidoptera are holometabolous insects, and their brains develop during the larval period and metamorphosis into the adult form. As the only fully domesticated insect, the Lepidoptera silkworm Bombyx mori experienced changes in larval brain morphology and certain behaviors during the domestication process. Hormonal regulation in insects is a key factor in multiple processes. However, how juvenile hormone (JH) signals regulate brain development in Lepidoptera species, especially in the larval stage, remains elusive. We recently identified the JH receptor Methoprene tolerant 1 ( Met1) as a putative dome

SUBMITTER: Cui Y 

PROVIDER: S-EPMC8455460 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature