Exploring reward-related attention selectivity deficits in Parkinson's disease.

ABSTRACT: An important aspect of managing a limited cognitive resource like attention is to use the reward value of stimuli to prioritize the allocation of attention to higher-value over lower-value stimuli. Recent evidence suggests this depends on dopaminergic signaling of reward. In Parkinson's disease, both reward sensitivity and attention are impaired, but whether these deficits are directly related to one another is unknown. We tested whether Parkinson's patients use reward information when automatically allocating their attention and whether this is modulated by dopamine replacement. We compared patients, tested both ON and OFF dopamine replacement medication, to older controls using a standard attention capture task. First, participants learned the different reward values of stimuli. Then, th

SUBMITTER: Pilgrim MJD 

PROVIDER: S-EPMC8455525 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature