Ontology highlight
ABSTRACT:
SUBMITTER: Schrott R
PROVIDER: S-EPMC8455898 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Schrott Rose R Murphy Susan K SK Modliszewski Jennifer L JL King Dillon E DE Hill Bendu B Itchon-Ramos Nilda N Raburn Douglas D Price Thomas T Levin Edward D ED Vandrey Ryan R Corcoran David L DL Kollins Scott H SH Mitchell John T JT
Environmental epigenetics 20210921 1
Cannabis use alters sperm DNA methylation, but the potential reversibility of these changes is unknown. Semen samples from cannabis users and non-user controls were collected at baseline and again following a 77-day period of cannabis abstinence (one spermatogenic cycle). Users and controls did not significantly differ by demographics or semen analyses. Whole-genome bisulfite sequencing identified 163 CpG sites with significantly different DNA methylation in sperm between groups (<i>P</i> < 2.94 ...[more]