Protocol for chemically induced murine gastric tumor model.
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ABSTRACT:
SUBMITTER: Li K
PROVIDER: S-EPMC8456110 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Publications
Protocol for chemically induced murine gastric tumor model.
Li Ke K Wang Ao A Liu Huijuan H Li Baojie B
STAR protocols 20210917 4
N-Methyl-N-nitrosourea, an N-nitroso compound converted from dietary nitrite by <i>Helicobacter pylori</i>, causes somatic mutations in epithelial cells and induces gastric premalignancy. Here, we describe a detailed protocol for induction of gastric tumor and analysis of tumor phenotypes in mice. This model can be widely used for studying the initiation and growth of gastric cancer. For complete details on the use and execution of this protocol, please refer to Li et al. (2021). ...[more]
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