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Xerostomia-related quality of life for patients with oropharyngeal carcinoma treated with proton therapy.


ABSTRACT:

Purpose

We report longitudinal patient-reported quality-of-life (QoL) outcomes related to xerostomia in patients with oropharyngeal cancer treated with intensity-modulated proton therapy (IMPT).

Materials and methods

Patients treated from May 2012 through December 2016 at a single institution for AJCC7 stage III-IV, M0 oropharyngeal cancer were given the 15-item Xerostomia-Related QoL Scale (XeQoLS) before, during, and for up to 2 years after treatment. We evaluated the evolution of xerostomia-related QoL over that time, and examined potential associations between those measures with clinical characteristics.

Results

Sixty-nine patients had XeQoLS scores at baseline and at least once either during or after treatment. The mean (±SD) XeQoLS score (0-4) was 0.24 ± 0.57 a

SUBMITTER: Bagley AF 

PROVIDER: S-EPMC8457365 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature