Double diffusion for the programmable spatiotemporal patterning of multi-domain supramolecular gels.

ABSTRACT: To achieve spatial resolution of a multi-component gel, a double diffusion approach is used which enables the precise programming of self-assembled patterned domains with well-defined shapes and sizes. The low-molecular-weight gelators (LMWGs) used in this study are pH-responsive DBS-CO₂H and thermally-responsive DBS-CONHNH₂ (both based on 1,3:2,4-dibenzylidenesorbitol, DBS). A DBS-CONHNH₂ gel was initially assembled in a tray, and then loaded at carefully-selected positions with either basified DBS-CO₂H (i.e. DBS-carboxylate) or an acid. These soluble components subsequently diffuse through the pre-formed gel matrix, and in the domains when/where they mix, protonation of the DBS-carboxylate induces self-assembly of the DBS-CO₂H

SUBMITTER: Cooke HS 

PROVIDER: S-EPMC8457394 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature