Sarcopenia increases the risk of post-operative recurrence in patients with non-small cell lung cancer.

ABSTRACT:

Background

Sarcopenia is among the most prevalent and serious cancer-related symptom, and is strongly correlated with a poor prognosis. Moreover, it reportedly predicts poor prognosis after surgery in patients with lung cancer. However, it is unclear whether sarcopenia directly affects post-operative recurrence. The purpose of this study was to evaluate whether sarcopenia can be a risk indicator for post-operative recurrence, and whether it suppresses anti-tumor immunity, in a cohort of patients with resected non-small cell lung cancer.

Methods

This study retrospectively reviewed the data of 256 consecutive patients who underwent curative lobectomy and lymph node dissection for non-small cell lung cancer at our institution. The psoas muscle mass index was calculated as the t

SUBMITTER: Kawaguchi Y 

PROVIDER: S-EPMC8457491 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature