Right ventricular function and vasoactive peptides for early prediction of bronchopulmonary dysplasia.

ABSTRACT:

Background

To assess the prognostic value of early echocardiographic indices of right ventricular function and vasoactive peptides for prediction of bronchopulmonary dysplasia (BPD) or death in very preterm infants.

Methods

Prospective study involving 294 very preterm infants (median [IQR] gestational age 28.4 [26.4-30.4] weeks, birth weight 1065 [800-1380] g), of whom 57 developed BPD (oxygen supplementation at 36 weeks postmenstrual age) and 10 died. Tricuspid annular plane systolic excursion (TAPSE), right ventricular index of myocardial performance (RIMP), plasma concentrations of mid-regional pro-atrial natriuretic peptide (MR-proANP) and C-terminal pro-endothelin-1 (CT-proET1) were measured on day 7 of life.

Results

RIMP was significantly increased (median [IQR]

SUBMITTER: Neumann RP 

PROVIDER: S-EPMC8457497 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature