Characterizing Sex Differences in Physical Frailty Phenotypes in Heart Failure.

ABSTRACT:

Background

Although women with heart failure (HF) are potentially more likely to be physically frail compared with men with HF, the underlying contributors to this sex difference are poorly understood. The purpose of this study was to characterize sex differences in physical frailty phenotypes in HF.

Methods

We prospectively enrolled adults with class I-IV HF. Physical frailty was measured with the frailty phenotype criteria. Symptoms of dyspnea, sleep-related impairment, pain interference, depression, and anxiety were assessed. Body composition was measured using dual-energy x-ray absorptiometry. Simple comparative statistics and stepwise regression modeling were used.

Results

The average age of the sample (n=115) was 63.6±15.7 years, 49% were women, and 73% had noni

SUBMITTER: Denfeld QE 

PROVIDER: S-EPMC8458254 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature