Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis.

ABSTRACT:

Objective

To evaluate the efficacy and safety of antiviral antibody therapies and blood products for the treatment of novel coronavirus disease 2019 (covid-19).

Design

Living systematic review and network meta-analysis, with pairwise meta-analysis for outcomes with insufficient data.

Data sources

WHO covid-19 database, a comprehensive multilingual source of global covid-19 literature, and six Chinese databases (up to 21 July 2021).

Study selection

Trials randomising people with suspected, probable, or confirmed covid-19 to antiviral antibody therapies, blood products, or standard care or placebo. Paired reviewers determined eligibility of trials independently and in duplicate.

Methods

After duplicate data abstraction, we performed random effects bayesian

SUBMITTER: Siemieniuk RA 

PROVIDER: S-EPMC8459162 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature