Genetic architecture and major genes for backfat thickness in pig lines of diverse genetic backgrounds.

ABSTRACT:

Background

Backfat thickness is an important carcass composition trait for pork production and is commonly included in swine breeding programmes. In this paper, we report the results of a large genome-wide association study for backfat thickness using data from eight lines of diverse genetic backgrounds.

Methods

Data comprised 275,590 pigs from eight lines with diverse genetic backgrounds (breeds included Large White, Landrace, Pietrain, Hampshire, Duroc, and synthetic lines) genotyped and imputed for 71,324 single-nucleotide polymorphisms (SNPs). For each line, we estimated SNP associations using a univariate linear mixed model that accounted for genomic relationships. SNPs with significant associations were identified using a threshold of p < 10^-6 and used to de

SUBMITTER: Gozalo-Marcilla M 

PROVIDER: S-EPMC8459476 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature