Vasoactive agents in acute mesenteric ischaemia in critical care.  A systematic review.

ABSTRACT: Background: Acute mesenteric ischaemia (AMI) is a surgical emergency which has an associated high mortality.  The mainstay of active treatment includes early surgical intervention, with resection of non-viable bowel, and revascularisation of the ischaemic bowel where possible. Due to the physiological insult of AMI however, perioperative care often involves critical care and the use of vasoactive agents to optimise end organ perfusion. A number of these vasoactive agents are currently available with varied mechanism of action and effects on splanchnic blood flow. However, specific guidance on which is the optimal vasoactive drug to use in these settings is limited. This systematic review aimed to evaluate the current evidence comparing vasoactive drugs in AMI. Methods: A syst

SUBMITTER: Brennan CA 

PROVIDER: S-EPMC8459625 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature