Ontology highlight
ABSTRACT:
SUBMITTER: Di Russo J
PROVIDER: S-EPMC8460267 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Di Russo Jacopo J Young Jennifer L JL Wegner Julian Wr JW Steins Timmy T Kessler Horst H Spatz Joachim P JP
eLife 20210923
Nanometer-scale properties of the extracellular matrix influence many biological processes, including cell motility. While much information is available for single-cell migration, to date, no knowledge exists on how the nanoscale presentation of extracellular matrix receptors influences collective cell migration. In wound healing, basal keratinocytes collectively migrate on a fibronectin-rich provisional basement membrane to re-epithelialize the injured skin. Among other receptors, the fibronect ...[more]