Additive Effect of Periodontal Disease and Obesity on COVID-19 Outcomes.

ABSTRACT: This study aims to examine the impact of periodontal disease in obesity on COVID-19 infection and associated outcomes. This retrospective longitudinal study included 58,897 UK Biobank participants tested for COVID-19 between March 2020 and February 2021. Self-reported oral health indicators (bleeding gums, painful gums, and loose teeth) were used as surrogates for periodontal disease. Body fat levels were quantified by body mass index (BMI) and categorized as normal weight (18.5 to 24.9 kg/m²), overweight (25 to 29.9 kg/m²), and obese (≥30 kg/m²). Multivariable logistic regression and Cox proportional hazard models were used to quantify risk of COVID-19 infection, hospital admission, and mortality, adjusted for participants' demographics and covariates. Of

SUBMITTER: Larvin H 

PROVIDER: S-EPMC8461046 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature